|
We Update Daily!
 Custom Search
Chris S. Kenoyer. Owner
MMJ Patient, Medical Activist,
Online Patients Advocate,
Online MMJ News Journalist
My Medical Bio
Follow Us Now On Twitter
@MedicalMMJMan
Or Follow Us Now
On Facebook
Email Us Here
olpwebs@yahoo.com
Or Email Us Securely Here
MedicalMMJMan@countermail.com
NEW 100% Encrypted Email Server
OLP’s Free MMJ News EList
Get The Latest In MMJ News
Press Contact Info
Is CBD? A Possible Cure For
Breast Cancer..? And All The Other
Many Forms & Types Of Cancer..?
Learn More About CBD Here
***************************
Advertise Here On OnlinePot
Rates As Low As $50 a Year
24/7 – 365 Days A Year Of Sales!
***********************************
Website Navigational Links
Main Start Page 2
**************************
Latest Marijuana News Reports
*********************************
Parody’s Cartoons US
Government Grown Pot,
Term Papers, School
Reports, & Thesis’s On
Marijuana & Cannabis
*********************************
Amsterdam A to Z
********************************
Canadian Marijuana Websites
*******************************
Church’s & Pot Cannabis
*****************************
Co-Ops, Clinics, Dispensary’s
*****************************
Marijuana Doctors & Clinics
****************************
Pot Cooking Recipes
****************************
Drug Testing A To Z
***************************
Pot Games
****************************
Pot Songs Video’s
****************************
100’s Of Grow Guides
***************************
Hash A- Z
***************************
Cannabis Legal Info, Drug
Lawyers, State, Federal Laws,
State & Supreme Court Rulings
**********************
POW’s Of The MMJ War!
*****************************
Other Marijuana Websites
Reciprocal Link Exchange
****************************
Medical Marijuana Studies,
Research Report’s, Medical
Cannabis Clinic Study’s
****************************
Parody’s & Cartoons
When We All Need A Good Laugh!
****************************
Avoiding Online MOM Scammers
Newly Re-Updated Info!
*****************************
The Politics Of Contraband
Medical Marijuana In The Mail?
******************************
The Hall Of Shame Section
The Online MOM Scammers
*****************************
Online MOM Providers Ads
****************************
Politicians & Voters Rights
****************************
Medical Marijuana, Strains
****************************
The OG Marijuana Strain Guide
****************************
800+ FAQ Growing Questions
****************************
Patients Spiritual Guidance,
Free Online Crisis Help Center
****************************
Online Marijuana Seed Banks
****************************
Maximum Security Section
Just Updated!
*****************************
Traveling Tips, Guides, B & B’s
****************************
Vaporizers A To Z
*****************************
Online Pot Video’s & Movies
**********************************************
Please Visit Both Of Our Sister Websites!
Maine Patients Coalition.org
The Reefer Madness Teaching Museum.org
Listen Right Here Online!
To Original 1930-1950’s
Reefer Madness Propaganda
Radio Shows And Programs
Before TV There Were
"Radio Stars"
*********************************
Legal Disclaimer
Guest Book
Translate Text or Web Page Go To:
Language Tools Google Translations
Article Submissions & News
Reports Are Always Gladly
Accepted Here.
No part of this site maybe used or
reproduced in whole or in part
without the written consent of the
Copyright Owner
www.onlinepot.org
OLP ENTERPRISES L3C
1999-2014 Copyright
© All rights reserved
OnlinePot assumes no legal liability for any products, or information or
news posted, services offered, Or
any contests or give away’s offered.
|
|
The Endocannabinoid System as a Possible Target
for Treating Post-Traumatic Stress Disorder
Return Back To OnlinePot’s Main Medical Page
Around 15-35% of those who experience serious trauma are likely to develop post-traumatic stress disorder (PTSD), and among those who have experienced abuse, neglect, or other adversity in childhood, the number tends toward the high end. Of those who develop PTSD , more than a third will fail to recover even after many years of therapy and medications (Darves-Bornoz et al., 2008). These people demonstrate considerable impairments in their overall quality of life, including physical health and psycho-social functioning (Schelling et al., 1998).
Obviously, the current treatment approaches (SSRI antidepressants, cognitive-behavioral therapy, and exposure therapy) are not working for a significant number of people.
One of the innovations in recent years has been the use of beta-blockers (high blood pressure medication) to reduce anxiety, hypervigilance, flashbacks, and nightmares. The one I see most often is Prazosin, which seems to work, in part, by reducing adrenaline levels, thereby decreasing anxiety.
Prazosin is an alpha-adrenergic blocker originally used to treat hypertension. "The reason we think it works in the setting of nightmares is that prazosin crosses the blood–brain barrier, so it gets into the brain and kind of dampens the norepinephrine effects, which we think contribute to nightmares," Dr. King said.
In my experience, the side-effects of this medication are far less intrusive and long-lasting than those of the SSRI and SNRI medications. The benefits, even if it is only improved sleep can be considerable for those who are good responders.
In this new article from Frontiers in Behavioral Neuroscience, the authors propose that a potential target for treating the anxiety and hypervigilance symptoms, as well as many of the other symptoms (avoidance, arousal, and re-experiencing), is the endocannabinoid system. A quick Google Scholar search turned up a lot of research in this area, including these articles:
- Fraser, GA. (2009). The Use of a Synthetic Cannabinoid in the Management of Treatment-Resistant Nightmares in Posttraumatic Stress Disorder (PTSD). CNS Neuroscience & Therapeutics, 15; 84–88. doi: 10.1111/j.1755-5949.2008.00071.x
- Hill, MN and Gorzalka, BB. (2009). The Endocannabinoid System and the Treatment of Mood and Anxiety Disorders. CNS & Neurological Disorders – Drug Targets, 8, 451-458.
My issue with this Frontiers article is that the authors don’t even mention possible treatments for PTSD that do not involve a pill. While I have many clients who need medication, at least in the short term, in order to get benefit from therapy, I have many who do not need medications, or who have enough affect regulation to manage the difficult symptoms when they come up.
No matter how many cool drugs are developed, we should always try to treat people without drugs first and foremost. Even with the medications that seem to have few side effects, such as the concepts proposed below, there are ALWAYS side effects.
The endocannabinoid system regulates memory, appetite, energy balance/metabolism, stress response, immune functions, pain perception, body temperature, and even neurogenesis. There is no way we can manipulate this system for one outcome and not impact its functions in other areas of the body.
Full Citation:
Trezza V and Campolongo P. (2013, Aug 9). The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD). Frontiers in Behavioral Neuroscience, 7:100. doi: 10.3389/fnbeh.2013.00100
Return Back To OnlinePot’s Main Medical Page
|
Button Ads! 