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Experts Call For Legal Cannabis To Treat Hep C Virus
Toronto, Ontario: Patients afflicted with the hepatitis C
virus (HCV) should be legally permitted to use cannabis
to combat treatment-related side effects of
the disease,
advises an international team of investigators writing in
the October
issue of the European Journal of
Gastroenterology & Hepatology.
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Back To Main Medical Reports Page
The researchers issued their recommendation following the results of an
observational study by the University of California at San Francisco (UCSF) that
found that HCV patients who used cannabis were significantly more likely to
adhere
to their treatment regimen than patients who didn't use it.
Patients on HCV therapy medications typically report numerous adverse side
effects -
including fatigue, headaches, nausea, anorexia, depression, and insomnia that
cause
many of them to prematurely discontinue treatment.
Commenting on the study, investigators from Canada and Germany wrote that
cannabis'
"potential benefits of a higher likelihood of treatment success [for HCV
patients]
appear to outweigh [its] risks. ... Even before such effects are conclusively
established, HCV treatment patients ... desiring to aid their treatment
adherence by
cannabis use should be legally permitted in doing so."
Though survey data indicates that many HCV patients use cannabis therapeutically
to
treat both symptoms of the disease as well as the side effects of HCV therapy,
no
clinical studies have been performed to assess the safety or efficacy of
cannabinoids for hepatitis C treatment. In addition, a 2005 retrospective study
of
untreated HCV patients reported that daily cannabis smoking was associated with
hepatic fibrosis. However, UCSF investigators found "no significant
difference in
liver fibrosis" between moderate cannabis smokers and non-users in their
observational study.
For more information, please contact Paul Armentano, NORML Senior Policy
Analyst, at
(202) 483-5500. Full text of studies, "Treatment for hepatitis C virus and
cannabis
use in illicit drug user patients: implications and questions" and
"Cannabis use
improves retention and virological outcomes in patients treated for hepatitis
C,"
are available in the October issue of the European Journal of Gastroenterology
&
Hepatology.
Additional information on cannabinoids and hepatitis C is available in NORML's
new
report, "Emerging Clinical Applications for Cannabis," online at:
http://www.norml.org/index.cfm?Group_ID=7002.
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