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  Smokeless Cannabis Vaporizers Delivery
 Systems Found Safer And Effective
 

 

Research Study Proves San Francisco, CA: Vaporization is a safer and effective cannabinoid delivery mode for patients who desire the rapid onset of action associated with inhalation while avoiding  the respiratory risks of smoking, according to clinical trial data to be published in the journal Clinical Pharmacology Therapeutics.

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               4-18-07

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         Marijuana Cannabis Vaporizers!

         STUDY SHOWS VAPORIZER'S CAN   
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      Water Pipe and Vaporizer Study

      How To Make A Marijuana Vaporizer



Investigators at San Francisco General Hospital 
reported that use of the Volcano vaporizing 
device delivered doses of THC to 
subjects in a  manner while 
significantly reducing their intake of gaseous 
combustion toxins, including carbon monoxide. 
Eighteen subjects participated in the six-day 
study, which was sponsored by the state of 
California and the Center 
for Medicinal Cannabis Research.

http://www.cmcr.ucsd.edu/geninfo/index.htm

Vaporization of marijuana does not result in 
exposure to combustion gases, ... and [was] 
preferred by most subjects compared to marijuana 
cigarettes,  authors concluded. & The Volcano 
[vaporizer] device is an effective and apparently 
safe vehicle for THC delivery, and warrants 
further investigation in clinical trials of 
cannabis for medical purposes.

Researchers reported that vaporization resulted 
in higher plasma concentrations of THC compared 
to smoked cannabis for up to 60 minutes following 
inhalation. Investigators also reported that 
subjects 'self-titrated' their intake of cannabis 
vapor, taking smaller and less frequent puffs 
when exposed to stronger marijuana. On average, 
the Volcano vaporizer exposed subjects to 54 
percent of the applied dose of THC. 
http://www.maps.org/news-letters/v06n3/06359mj1.html

Previous studies have shown that as much as 80 percent of 
the THC burned in cigarettes or water-pipes is 
lost in slipstream smoke.

A www.norml.org/index.cfm?Group_ID=6885
clinical trial assessing the safety and efficacy 
of the Volcano vaporizer published in 2006 in the 
Journal of Pharmaceutical Sciences also reported 
that the device delivers set doses of THC to 
subjects in a reproducible manner & while avoiding 
the respiratory disadvantages of smoking. The 
efficacy of the Volcano vaporizer was initially 
reported in a study co-sponsored by NORML 

  http://www.canorml.org/healthfacts/vaporizerstudy2.html

and the Multidisciplinary Association for Psychedelic Studies (MAPS), which 
found that the device delivered vapor of high 
purity with practically no toxic tars or 
hydrocarbons.

Vaporization heats cannabis to a temperature 
where active cannabinoid vapors form (typically 
around 180-190 degrees Celsius), but below the 
point of combustion where noxious smoke and 
associated toxins (i.e., carcinogenic 
hydrocarbons) are produced (above 230 degrees 
Celsius).

Separate survey data published this week in the 
Harm Reduction Journal also reports that 
vaporization is subjectively associated with 
fewer respiratory symptoms than smoking cannabis.


Abstracts of the study, & Decreased respiratory 
symptoms in cannabis users who vaporize,& are 
available online at:
  http://www.harmreductionjournal.com/content/4/1/11/abstract


Pot's Active Ingredient Halts Lung Cancer Growth, Study Says



Los Angeles, CA: The 
administration of THC significantly reduces lung 
tumor size and lesions, according to preclinical 
data presented this week at the annual meeting of 
the American Association for Cancer Research 
(AACR) in Los Angeles. 

Investigators at Harvard University's Division of 
Experimental Medicine reported that THC inhibited 
the growth and spread of cells in vitro from two 
different lung cancer cell lines and from patient 
lung tumors. They also reported that THC 
administration reduced the growth of lung tumors 
in mice by more than 50 percent compared to 
untreated controls over a three-week period.

Researchers noted that THC appeared to block a 
specific cancer-causing protein in a manner 
similar to the pharmaceutical anti-cancer drugs 
Erbitux (Cetuximab) and Vectibix (Panitumumab).

Results of a large-scale, case-controlled 

http://www.norml.org/index.cfm?Group_ID=6912

study published last year found that smoking 
cannabis, even long-term, is not positively 
associated with increased incidence of 
lung-cancer. Investigators in that study noted 
that one subset of moderate lifetime users had an 
inverse association between cannabis use and lung 
cancer, leading them to speculate that 
cannabinoids may possess certain protective 
properties against the development of lung cancer 
in humans.

Separate  http://www.norml.org/index.cfm?Group_ID=7008
pre-clinical studies indicate that compounds in marijuana 
inhibit cancer cell growth in animals and in 
culture on a wide range of tumoral cell lines -- 
including human breast carcinoma cells, human 
prostate carcimona cells, and human colectoral 
carcinoma cells, among others. Most recently, 
investigators at Madrid's Complutense University, 
School of Biology, reported in the British 
Journal of Cancer that 

http://www.norml.org/index.cfm?Group_ID=6947
administration decreases  recurrent glioblastoma multiforme 
(brain) tumor growth in patients diagnosed with the disease.

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