The CBD compound found in cannabis is non-toxic
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A compound found in cannabis 'CBD' may stop breast cancer spreading
throughout the body, US scientists believe.
ONLINEPOT NEWS REPORT EXPOSE'
The California Pacific Medical Center Research Institute team are
hopeful that cannabidiol or CBD could be a non-toxic alternative to
chemotherapy.
Unlike cannabis, CBD does not have any psychoactive properties so its
use would not violate laws, Molecular Cancer Therapeutics reports.
The authors stressed that they were not suggesting patients smoke
marijuana.
They added that it would be highly unlikely that effective
concentrations of CBD could be reached by smoking cannabis.
CBD works by blocking the activity of a gene called Id-1 which is
believed to be responsible for the aggressive spread of cancer cells away
from the original tumour site - a process called metastasis.
Past work has shown CBD can block aggressive human brain cancers.
The latest work found CBD appeared to have a similar effect on breast
cancer cells in the lab.
Future hope
Lead researcher Dr Sean McAllister said: "Right now we have a
limited range of options in treating aggressive forms of cancer.
"Those treatments, such as chemotherapy, can be effective but they
can also be extremely toxic and difficult for patients.
"This compound offers the hope of a non-toxic therapy that could
achieve the same results without any of the painful side effects."
Dr Joanna Owens of Cancer Research UK said: "This research is at a
very early stage.
"The findings will need to be followed up with clinical trials in
humans to see if the CBD is safe, and whether the beneficial effects can
be replicated.
"Several cancer drugs based on plant chemicals are already used
widely, such as vincristine - which is derived from a type of flower
called Madagascar Periwinkle and is used to treat breast and lung cancer.
It will be interesting to see whether CBD will join them."
Maria Leadbeater of Breast Cancer Care said: "Many people
experience side-effects while having chemotherapy, such as nausea and an
increased risk of infection, which can take both a physical and emotional
toll.
"Any drug that has fewer side-effects will, of course, be of great
interest."
But she added: "It is clear that much more research needs to be
carried out."
http://news.bbc.co.uk/2/hi/health/7098340.stm
Currently "Only" the UK is currently running medical
testing
with CBD on 'Live Breast Cancer Patients". & Given the USA
past history with "Cannabis Based Drug" 
I would not expect them to due any "Medical CBD Testing" here in
the USA on Any "Live Breast Cancer Patient Subjects" For many
many years from now! Ball Park 10 to 15 Years Min! Which
in my thought that how many 10,000 to 100,000 US Based
Cancer Arte Going To DIE! Before The US Administration
& The FDA gets off their butts. & Start testing this derivative
of the Cannabis Plant on the sick & dieing Cancer patients
here in the US
I am no Doctor Or A Scientist But I personally have seen 1
lady that Breast Cancer is litterly "Eating Its Way Thru Her
Entire Family" 1 dead all ready, 1 more in the hospital has I type
this dieing, another being told that they need to remove a breast, &
This lady who 3 days before Xmas got that bad news
that she has a cancer lump in her beast, Which was causing a great pain on
her breast nipple, & That within 8 to 10 days, Of starting the CBD
Treatment, That pain in her breast nipple was GONE!
I am NOT a DR! I am NOT saying this is a miracle cure!
I am just saying that "The Scientists Here in The USA"
Needs To Start Testing this CBD Right NOW!
How many more cancer patients are going to have to die?
Before the USA
Gets off its butt & instructs the FDA to get the "Live USA Cancer
Patients Medical Testing" going on CBD "ASAP!
CDB doesn't even get
you high, There Is
ZERO Physcotropics in CBD!
Sincerely Chris/OLP
CBD
OIL IS NOW AVAILABLE ONLINE
Meet your own underground med MMJ in Canada on the Internet. I
have made the CBD for the British MS patients. And the olive oil which is
very easy to use. I use 10 grams per bottle and the Canadian clubs swear
by it in their cooking. This CBD does not have the terrible taste when
used in cooking recipes. like you get when you use “Canna
Butter”. Once they started using it we heard a lot of misdiagnosed
cancer stories. I have a 80% reorder rate from cancer and MS patients.
They use it for pain. 7-27-08
Contact Sunny at sunny123@hush.com
RELATED INTERNET LINKS
http://en.wikipedia.org/wiki/Cannabidiol
Another Article About CBD
Cannabidiol, also known as CBD, is a
cannabinoid found in Cannabis. It is a major constituent of the plant,
representing up to 40% in its extracts.[1]
CBD alone is not intoxicating, but it
appears to moderate the euphoric effect of tetrahydrocannabinol (THC),
which is an isomer of cannabidiol and add a sedative quality.[2] Some
research, however, indicates that CBD can increase alertness.[3] It may
decrease the rate of THC clearance from the body, perhaps by interfering
with the metabolism of THC in the liver. CBD does not appear to affect
either the CB1 or CB2 receptors.[4]
Medically, it appears to relieve
convulsion, inflammation, anxiety, and nausea, and to inhibit cancer cell
growth.[5] Recent studies have shown cannabidiol to be as effective as
atypical antipsychotics in treating schizophrenia.[6] In November 2007 it
was reported that CBD reduces growth of aggressive human breast cancer
cells in vitro and reduces their invasiveness. It thus represents the
first non-toxic exogenous agent that can lead to down-regulation of tumor
aggressiveness.[7][8] It is also a neuroprotective antioxidant.[9]
Medicinal use
In April 2005, Canadian authorities
approved the marketing of Sativex, a mouth spray for multiple sclerosis to
alleviate pain. Sativex contains tetrahydrocannabinol together with
cannabidiol. It is marketed in Canada by GW Pharmaceuticals.
Initial research is showing that CBD has
an effect in reducing schizophrenic symptoms in patients.[10]
Pharmacology
Cannabidiol does not bind to CB1 or CB2
receptors but it does block the effects of cannabinoid agonists by an
unknown indirect way.[11] Recently it was found to be an antagonist at the
putative new cannabinoid receptor, GPR55, a GPCR expressed in the caudate
nucleus and putamen.[12]
Cannabidiol has also been shown to
inhibit cancer cell growth, with low potency in non-cancer cells. Although
the inhibitory mechanism is not yet fully understood, Ligresti et al
suggest that "cannabidiol exerts its effects on these cells through a
combination of mechanisms that include either direct or indirect
activation of CB2 and TRPV1 receptors, and induction of oxidative stress,
all contributing to induce apoptosis."[13] In November 2007,
researchers at the California Pacific Medical Center reported that CBD
shows promise for controlling the spread of metastatic breast cancer. In
vitro CBD down regulates the activity of the gene Id-1 which is
responsible for tumor metastasis.[7]
Chemistry
Cannabidiol is insoluble in water but
soluble in organic solvents. At room temperature it is a colorless
crystalline solid.[14] In strongly basic medium and the presence of air it
is oxidized to a quinone.[15] Under acidic conditions it cyclizes to
THC.[16] The synthesis of cannabidiol has been accomplished by several
research groups.[17][18][19]
Legal Status
Cannabidiol is a Schedule I drug in the
USA, despite having no psychoactive effects and no known abuse potential.
The strict legal status may be due to the fact that CBD has been shown to
inhibit the anxiety that THC can induce at high doses ~0.5mg/kg[20] and
also how easily CBD could be converted to THC, as outlined above.
From http://www.michiganmedicalmarijuana.org/node/1492
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This compound offers the hope of a non-toxic therapy that
could achieve the same results without any of the painful side
effects 