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Cannabis use improves outcome of antiviral treatment in patients with hepatitis C
Drug addicts who are infected with hepatitis C virus may continue their medication until the planned treatment end more often if they use cannabis and may have a better treatment outcome, scientists of the University of California reported in the European Journal of Gastroenterology and Hepatology.
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Cannabis may help them tolerate the side effects of the antivirals, which can clear the virus but often cause fevers, chills, and muscle and joint aches, the researchers said.
Dr. Diana Sylvestre and colleagues tested 71 patients given interferon and ribavirin to treat their hepatitis C. Interferon boosts the immune response and ribavirin attacks the virus. 22 of them (31 per cent) also used cannabis. 24 per cent of all patients discontinued therapy early, among them only one cannabis user but 16 non-users. About half of the cannabis users (54 per cent) were successfully treated with the medication, which means that the virus was no longer detectable, compared to only 18 per cent of the control group. And just 14 per cent of the cannabis users relapsed, compared to 61 per cent of non- users. Relapse means that the hepatitis C virus was detectable again after a while.
Researchers concluded that these "results suggest that modest cannabis use may offer symptomatic and virological benefit to some patients undergoing HCV treatment by helping them maintain adherence to the challenging medication regimen."
(Sources: Reuters of 13 September 2006; Sylvestre DL, Clements BJ, Malibu Y. Cannabis use improves retention and virological outcomes in patients treated for hepatitis C. Eur J Gastroenterol Hepatol 2006;18(10):1057-63.)
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